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Physicians should advise patients to stop use of all phosphodiesterase type 5 (PDE5) inhibitors, including Viagra, and seek medical attention in the event of a sudden loss of vision in one or both eyes. Such an event may be a sign of non-arteritic anterior ischemic optic neuropathy (NAION), a rare condition and a cause of decreased vision including permanent loss of vision, that has been reported rarely post-marketing in temporal association with the use of all PDE5 inhibitors. Based on published literature, the annual incidence of NAION is 2.5–11.8 cases per 100,000 in males aged ≥ 50. An observational study evaluated whether recent use of PDE5 inhibitors, as a class, was associated with acute onset of NAION. The results suggest an approximate 2 fold increase in the risk of NAION within 5 half-lives of PDE5 inhibitor use. From this information, it is not possible to determine whether these events are related directly to the use of PDE5 inhibitors or to other factors [see Adverse Reactions (6.2)]. viagra price Levitra 10 mg Label59 users found this comment helpful. Did you? Yes No Report as inappropriate

DRUG CLASS AND MECHANISM: Viagra (sildenafil) is an oral drug that is used for treating impotence (or erectile disfunction, ED, the inability to attain or maintain a penile erection). It is in a class of drugs called phosphodiesterase inhibitors (PDE-5 inhibitors) that also includes Significant improvements in the EF Domain were shown in this study (EF Domain scores of 17 on 10 mg Levitra and 19 on 20 mg Levitra compared to 13 on placebo; p <0.0001).

The free Drugs Discount Card can save you up to 80% or more off the cost of prescription medicines, over-the-counter drugs and pet prescriptions.?sensitivity to light prescription drug information Tadalafil is excreted predominantly as inactive metabolites, mainly in the faeces (approximately 61% of the dose) and to a lesser extent in the urine (approximately 36% of the dose).Recommended AdministrationIt is best to see your GP. He or she is likely to discuss the problem, go over any medication you may be taking, and do a physical examination. This can help to identify or rule out possible underlying causes. Before treatment, your GP may suggest some tests.

Effects on Exercise Stress TestingSkin and Appendages — pruritus, rash, sweating does viagra make you last longer You should check with your doctor immediately if any of these side effects occur when taking vardenafil:

Sildenafil enhances the effect of NO by inhibiting phosphodiesterase type 5 (PDE5), which is responsible for degradation of cGMP in the corpus cavernosum. Sildenafil has no direct relaxant effect on isolated human corpus cavernosum. When sexual stimulation causes local release of NO, inhibition of PDE5 by sildenafil causes increased levels of cGMP in the corpus cavernosum, resulting in smooth muscle relaxation and inflow of blood to the corpus cavernosum. Sildenafil at recommended doses has no effect in the absence of sexual stimulation.

have any other heart or blood vessel problems. how to take levitra ? breathing problems some types of antibiotics, such as clarithromycin (Biaxin),

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