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Patients should be made aware that both alcohol and Cialis, a PDE5 inhibitor, act as mild vasodilators. When mild vasodilators are taken in combination, blood-pressure-lowering effects of each individual compound may be increased. Therefore, physicians should inform patients that substantial consumption of alcohol (e.g., 5 units or greater) in combination with Cialis can increase the potential for orthostatic signs and symptoms, including increase in heart rate, decrease in standing blood pressure, dizziness, and headache [see Clinical Pharmacology (12.2)].(N=97)

Cialis is indicated for the treatment of the signs and symptoms of benign prostatic hyperplasia (BPH).Distribution — The mean apparent volume of distribution following oral administration is approximately 63 L, indicating that tadalafil is distributed into tissues. At therapeutic concentrations, 94% of tadalafil in plasma is bound to proteins. average cost of cialis Be careful driving or operating machinery until you know how CIALIS affects you.Cialis InteractionsCialisIf you have a low sex drive, or if you have had a previous head injury, ED may be due to a hormonal problem. In this situation a blood test to check the level of the hormone testosterone (and sometimes prolactin) may be advised.

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Potential for Pharmacodynamic Interactions with Cialis Diabetes. This is one of the most common causes of ED. Diabetes can affect blood vessels and nerves.

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Stop using sildenafil and call your doctor at once if you have a serious side effect such as:Sudden Loss of Vision