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Non-arteritic anterior ischemic optic neuropathy (NAION), a cause of decreased vision including permanent loss of vision, has been reported rarely postmarketing in temporal association with the use of phosphodiesterase type 5 (PDE5) inhibitors, including Cialis. Most, but not all, of these patients had underlying anatomic or vascular risk factors for development of NAION, including but not necessarily limited to: low cup to disc ratio (“crowded disc”), age over 50, diabetes, hypertension, coronary artery disease, hyperlipidemia, and smoking. It is not possible to determine whether these events are related directly to the use of PDE5 inhibitors, to the patient's underlying vascular risk factors or anatomical defects, to a combination of these factors, or to other factors [see Warnings and Precautions (5.4)]. define viagra Once-a-day dosing of 2.5 or 5 mg tadalafil both for the treatment of erectile dysfunction or benign prostatic hyperplasia is not recommended in patients with severe renal impairment (see sections 4.4 and 5.2). swelling in your hands, ankles, or feet;Things You Didn't Know About Cialis

Across all studies with any Cialis dose, reports of changes in color vision were rare (<0.1% of patients).Setting The Record Straight: Erectile Dysfunction levitra super active

PRN use: Decrease dose with concomitant use of potent CYP3A4 inhibitor (eg, ritonavir, ketoconazole, itraconazole); not to exceed 10 mg/72 hr For pulmonary arterial hypertension patients, doses of 20, 40, and 60 mg may be prescribed. Typically, after 16 weeks of treatment, a 40 mg daily dose proved effective.

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Aspirin — Tadalafil did not potentiate the increase in bleeding time caused by aspirin.

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